Acetyl-Hirudin (55-65) (desulfated)
Names
[ CAS No. ]:
113274-57-0
[ Name ]:
Acetyl-Hirudin (55-65) (desulfated)
[Synonym ]:
ACETYL-HIRUDIN (55-65) (DESULFATED)
N-acetyl-hirudin fragment 55-65
ACETYL-ASP-PHE-GLU-GLU-ILE-PRO-GLU-GLU-TYR-LEU-GLN
AC-ASP-PHE-GLU-GLU-ILE-PRO-GLU-GLU-TYR-LEU-GLN-OH
ac-hirudin fragment 55-65 non-sulfated
N-ACETYL-HIRUDIN AC-FRAGMENT 55-65 NON-SULFATED
AC-ASP-PHE-GLU-GLU-ILE-PRO-GLU-GLU-TYR-LEU-GLN
Chemical & Physical Properties
[ Molecular Formula ]:
C66H92N12O25
[ Molecular Weight ]:
1453.50000
[ Exact Mass ]:
1452.63000
[ PSA ]:
598.43000
[ LogP ]:
1.95970
MSDS
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
Articles
Blood 95 , 1729-1734, (2000)
During sepsis, lipopolysaccharide (LPS) triggers the development of disseminated intravascular coagulation (DIC) via the tissue factor-dependent pathway of coagulation resulting in massive thrombin ge...
Thrombin-dependent MMP-2 activity is regulated by heparan sulfate.J. Biol. Chem. 285 , 41270-41279, (2010)
Like most metalloproteases, matrix metalloprotease 2 (MMP-2) is synthesized as a zymogen. MMP-2 propeptide plays a role in inhibition of catalytic activity through a cysteine-zinc ion pairing, disrupt...
Chemical compensation in macromolecular bridge-binding to thrombin.Biochemistry 32 , 2947-2953, (1993)
The binding energetics of eight synthetic peptides capable of interfering with thrombin function have been studied by steady-state measurements and clotting assays. The synthetic peptides are bifuncti...