MOPS

Names

[ Name ]:
MOPS

[Synonym ]:
MOPS
3-(Morpholin-4-ium-4-yl)propane-1-sulfonate
3-Morpholinopropanes
3-(N-Morpholino)propanesulfonic acid,4-Morpholinepropanesulfonic acid
MOPS ULTRAPURE
2-morpholinoethanesulfonic acid
4-Morpholinepropanesulfonic acid
3-(morpholin-4-yl)propane-1-sulfonic acid
MOPS low sodium
3-Morpholinopropanesulfoinc Acid
Morpholinopropane sulfonic acid
MFCD00006183
morpholinium propane sulfonate
EINECS 214-478-5
3-(Morpholin-4-ium-4-yl)-1-propanesulfonate
3-(N-Morpholino)Propanesulfonic Acid
3-morpholinopropanesulfonic acid
MOPS,BIOLOGICALBUFFER
3-Morpholinopropanesulfonic Acid [Good's buffer component
4-morpholinepropanesulphonic acid
3-Morpholinopropanesulfonic acid(MOPS)
WAS 15
MOPS FREE ACID
3-(Morpholin-4-ium-4-yl)propan-1-sulfonat
3-Morpholinopropane-1-sulfonic acid
3-(N-Morpholino)propanesulfonic acid,4-M
morpholino propane sulphonic acid
3-(4-Morpholino)propanesulfonic acid
3-Morpholinopropanesulfonicacid

Biological Activity

[Description]:

MOPS is commonly used as a buffering agent in biology. MOPS buffer can maintain the pH of mammalian cell culture media[1][2].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Steven D Carson, et al. MOPS and coxsackievirus B3 stability. Virology. 2017 Jan 15;501:183-187.

[2]. Juliane Schmidt, et al. Effect of Tris, MOPS, and phosphate buffers on the hydrolysis of polyethylene terephthalate films by polyester hydrolases. FEBS Open Bio. 2016 Jul 20;6(9):919-27.

Chemical & Physical Properties

[ Density]:
1.298 g/cm3

[ Melting Point ]:
277-282 °C

[ Molecular Formula ]:
C₇H₁₅NO₄S

[ Molecular Weight ]:
209.263

[ Flash Point ]:
116 °C

[ Exact Mass ]:
209.072174

[ PSA ]:
75.22000

[ LogP ]:
-1.91

[ Index of Refraction ]:
1.512

[ Storage condition ]:
Store at RT.

[ Stability ]:
Stable. Incompatible with strong bases, strong oxidizing agents.

[ Water Solubility ]:
1000 g/L (20 ºC)

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: QE9104530

CHEMICAL NAME :: 4-Morpholinepropanesulfonic acid

CAS REGISTRY NUMBER :: 1132-61-2

LAST UPDATED :: 199701

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C7-H15-N-O4-S

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Bird - quail

DOSE/DURATION :: >316 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: EESADV Ecotoxicology and Environmental Safety. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1977- Volume(issue)/page/year: 6,149,1982 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X7191 No. of Facilities: 174 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 1690 (estimated) No. of Female Employees: 1218 (estimated)

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
1

[ RTECS ]:
QE9104530

[ HS Code ]:
29349990

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Proteasome-mediated degradation of FRIGIDA modulates flowering time in Arabidopsis during vernalization.

Plant Cell 26(12) , 4763-81, (2015)

Winter-annual accessions of Arabidopsis thaliana require either exposure to cold stress or vernalization to initiate flowering via FRIGIDA (FRI). FRI acts as a scaffold protein to recruit several chro...

The Mtr4 ratchet helix and arch domain both function to promote RNA unwinding.

Nucleic Acids Res. 42(22) , 13861-72, (2014)

Mtr4 is a conserved Ski2-like RNA helicase and a subunit of the TRAMP complex that activates exosome-mediated 3'-5' turnover in nuclear RNA surveillance and processing pathways. Prominent features of ...

Antisense oligonucleotides capable of promoting specific target mRNA reduction via competing RNase H1-dependent and independent mechanisms.

PLoS ONE 9(10) , e108625, (2014)

Antisense oligonucleotides (ASOs) are most commonly designed to reduce targeted RNA via RNase H1-dependent degradation. In this paper we demonstrate that cellular proteins can compete for sites target...

Related Compounds

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