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Physalin L

Names

[ CAS No. ]:
113146-74-0

[ Name ]:
Physalin L

[Synonym ]:
1,17:2,6-Dimethano-8H-naphtho[1,2-f]furo[3,4-b:2,3-c']bisoxocin-4,8,11,19(1H,10H)-tetrone, 2,3,6,6a,8a,9,10a,10b,12,16,16a,17-dodecahydro-8a,16,17-trihydroxy-2,3,6a,10b-tetramethyl-, (1R,2S,3S,6R,6aS,8aS,10aS,10bR,16R,16aS,17R,18aR)-
(1S,2R,3R,5R,6S,7R,14R,15S,18S,21S,22R,25S)-5,7,18-Trihydroxy-1,14,21,25-tetramethyl-4,20,23-trioxaheptacyclo[20.3.1.1.0.0.0.0]heptacosa-8,10-diene-13,19,24,27-tetrone

Biological Activity

[Description]:

Physalin L inhibits LPS-induced NO production in macrophages with the average inhibitory rate of 70.97%. Anti-inflammatory activity[1].

[Related Catalog]:

Signaling Pathways >> Immunology/Inflammation >> NO Synthase

[References]

[1]. Long Ji, et al. Physalins with anti-inflammatory activity are present in Physalis alkekengi var. franchetii and can function as Michael reaction acceptors. Steroids. 2012 Apr;77(5):441-7.

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
831.1±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C28H32O10

[ Molecular Weight ]:
528.548

[ Flash Point ]:
280.4±27.8 °C

[ Exact Mass ]:
528.199524

[ PSA ]:
156.66000

[ LogP ]:
2.07

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.659

Related Compounds