FGF22-IN-1

Names

[ Name ]:
FGF22-IN-1

[Synonym ]:
N'-[(E)-1H-Indol-3-ylmethylene]-2-thiophenecarbohydrazide
N'-[(E)-1H-Indol-3-ylmethylene]thiophene-2-carbohydrazide
2-Thiophenecarboxylic acid, 2-[(1E)-1H-indol-3-ylmethylene]hydrazide

Biological Activity

[Description]:

FGF22-IN-1 (compound c1) is a potent CD4 D1 inhibitor. FGF22-IN-1 can be used as immunosuppressive agent[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Inflammation/Immunology

[Target]

CD4 D1[1]

[References]

[1]. Xiao H, et al. Potent inhibition of the CD4-dependent T cell response by J2, a novel nonpeptide organic ligand of CD4 D1. Mol Immunol. 2007 Feb;44(5):784-95.

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Molecular Formula ]:
C₁₄H₁₁N₃OS

[ Molecular Weight ]:
269.32

[ Exact Mass ]:
269.062286

[ LogP ]:
2.39

[ Index of Refraction ]:
1.707

Related Compounds

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