Ganoderic acid TN

Names

[ Name ]:
Ganoderic acid TN

[Synonym ]:
(3β,15α,24E)-15-Acetoxy-3-hydroxylanosta-7,9(11),24-trien-26-oic acid
Lanosta-7,9(11),24-trien-26-oic acid, 15-(acetyloxy)-3-hydroxy-, (3β,15α,24E)-

Biological Activity

[Description]:

Ganoderic acid T-N, a triterpenoid, is a H5N1 and H1N1 influenza neuraminidase (NA) inhibitor with IC50s of 2.7 μM and 42 μM, respectively. Ganoderic acid T-Q shows cytotoxicity against MCF7 cells (CC50=24.4 μM)[1].

[Related Catalog]:

Signaling Pathways >> Anti-infection >> Influenza Virus

Research Areas >> Infection

[References]

[1]. Qinchang Zhu, et al.Inhibition of neuraminidase by Ganoderma triterpenoids and implications for neuraminidase inhibitor design. Sci Rep. 2015 Aug 26;5:13194.

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
625.5±55.0 °C at 760 mmHg

[ Molecular Formula ]:
C₃₂H₄₈O₅

[ Molecular Weight ]:
512.721

[ Flash Point ]:
193.1±25.0 °C

[ Exact Mass ]:
512.350159

[ LogP ]:
7.87

[ Vapour Pressure ]:
0.0±4.1 mmHg at 25°C

[ Index of Refraction ]:
1.555

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.