4-Dimethylaminopyridine

Names

[ Name ]:
4-Dimethylaminopyridine

[Synonym ]:
4-Dimethylaminopyrid
N4,N4-dimethylpyridin-4-amine
N-(4-Pyridyl)dimethylamine
4-dimethylamino pyridine
26DCLPY
4-Dimethylaminopyridine
N,N-dimethylpyridin-4-amine
5-22-09-00112 (Beilstein Handbook Reference)
MFCD00006244
DMAP
DMAP solution
N,N-Dimethyl-4-pyridinamine
p-dimethylaminopyridine
EINECS 214-353-5
4-Pyridinamine, N,N-dimethyl-
4-Dimethylami
dimethylaminopyridine
AURORA KA-6495
4-Dimethylaminepyridine
4-(dimethylamino)pyridine
4-(Dimethylamino)pyridine,N,N-Dimethylpyridin-4-amine,DMAP
4-(N,N-dimethylamino)pyridine
UNII-PFP1R6P0S8
N,N-Dimethylpyridin-4-amine DMAP

Biological Activity

[Description]:

N-(4-pyridyl)dimethylamine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
162 ºC (50 mmHg)

[ Melting Point ]:
108-113 ºC

[ Molecular Formula ]:
C₇H₁₀N₂

[ Molecular Weight ]:
122.17

[ Flash Point ]:
110 ºC

[ Exact Mass ]:
122.084396

[ PSA ]:
16.13000

[ LogP ]:
1.34

[ Vapour Pressure ]:
0.4±0.4 mmHg at 25°C

[ Index of Refraction ]:
1.554

[ Storage condition ]:
Store in dark!

[ Stability ]:
Stable. Incompatible with acids, oxidizing agents.

[ Water Solubility ]:
76 g/L (25 ºC)

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: US9230000

CHEMICAL NAME :: Pyridine, 4-(dimethylamino)-

CAS REGISTRY NUMBER :: 1122-58-3

BEILSTEIN REFERENCE NO. :: 0110354

LAST UPDATED :: 199710

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C7-H10-N2

MOLECULAR WEIGHT :: 122.19

WISWESSER LINE NOTATION :: T6NJ DN1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 250 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0536502

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 470 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AECTCV Archives of Environmental Contamination and Toxicology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 070944) V.1- 1973- Volume(issue)/page/year: 14,111,1985

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 56 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#04228

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 13 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0536502

Safety Information

[ Symbol ]:

GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H301-H310-H315-H319-H335

[ Precautionary Statements ]:
Missing Phrase - N15.00950417-P262-P280-P302 + P352 + P310-P305 + P351 + P338-P361 + P364

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges

[ Hazard Codes ]:
T:Toxic

[ Risk Phrases ]:
R24/25;R34

[ Safety Phrases ]:
S36/37/39-S45-S28A-S26-S28-S36/37-S53-S27-S22

[ RIDADR ]:
UN 2811 6.1/PG 2

[ WGK Germany ]:
3

[ RTECS ]:
US8400000

[ Packaging Group ]:
II

[ Hazard Class ]:
8

[ HS Code ]:
2933399090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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