5-Iodocytosine
Names
[ CAS No. ]:
1122-44-7
[ Name ]:
5-Iodocytosine
[Synonym ]:
4-amino-5-iodo-1H-pyrimidin-2-one
6-Amino-5-iodpyrimidin-2(1H)-on
2(1H)-Pyrimidinone, 4-amino-5-iodo-
5-Iodocytosine
4-Amino-5-iodopyrimidin-2(1H)-one
CYTOSINE,5-IODO
4-Amino-5-iodo-2(1H)-pyrimidinone
6-amino-5-iodopyrimidin-2(1H)-one
MFCD00023162
5-IODO CYTOSINE
4-Amino-5-iodo-2-pyrimidinol
2-pyrimidinol, 4-amino-5-iodo-
4-Amino-2-hydroxy-5-iodopyrimidine
4-Amino-5-jod-1H-pyrimidin-2-on
4-Amino-5-iodopyrimidin-2-ol
Chemical & Physical Properties
[ Density]:
2.7±0.1 g/cm3
[ Boiling Point ]:
480.2ºC at 760mmHg
[ Molecular Formula ]:
C4H4IN3O
[ Molecular Weight ]:
236.999
[ Flash Point ]:
244.2ºC
[ Exact Mass ]:
236.939896
[ PSA ]:
71.77000
[ LogP ]:
-0.87
[ Vapour Pressure ]:
7.64E-10mmHg at 25°C
[ Index of Refraction ]:
1.852
[ Storage condition ]:
−20°C
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- HA6125000
- CHEMICAL NAME :
- Cytosine, 5-iodo-
- CAS REGISTRY NUMBER :
- 1122-44-7
- LAST UPDATED :
- 199012
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C4-H4-I-N3-O
- MOLECULAR WEIGHT :
- 237.01
- WISWESSER LINE NOTATION :
- T6MVNJ DZ EI
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 50 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 13,1249,1964
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H302
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xn
[ Risk Phrases ]:
R22
[ Safety Phrases ]:
24/25
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
HA6125000
[ HS Code ]:
2933599090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2933599090
[ Summary ]:
2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
Articles
PLoS ONE 4(3) , e4949, (2009)
Glycerol nucleic acid (GNA) has an acyclic phosphoglycerol backbone repeat-unit, but forms stable duplexes based on Watson-Crick base-pairing. Because of its structural simplicity, GNA is of particula...
Preparation and properties of oligodeoxynucleotides containing 5-iodouracil and 5-bromo- and 5-iodocytosine.Bioconjug. Chem. 8(5) , 757-61, (1997)
The behavior of oligonucleotides containing 5-iodouracil, 5-bromocytidine, and 5-iodocytidine in concentrated ammonia is described. 5-Aminouracil and 5-aminocytidine are obtained as side products when...
Photochemistry of halogen pyrimidines: iodine release studies.Photochem. Photobiol. 56(1) , 9-15, (1992)
The feasibility of using direct iodide (I-) measurements to monitor the photochemistry of the halogenated pyrimidines 5-iodocytosine and 5-iodouracil and their corresponding deoxynucleosides was exami...