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1-Tetradecanol

Names

[ CAS No. ]:
112-72-1

[ Name ]:
1-Tetradecanol

[Synonym ]:
teradecyl alcohol
Myristic alcohol
n-Tetradecyl alcohol
Tetradecyl alcohol
1-Tetradecanol
n-tetradecyl acrylate
Myristyl alcohol
n-Tetradecanol
Nacol 14-95
Acrylsaeure-tetradecylester
Acrylsaeure-n-tetradecylester
Tetradecanol
2-Propenoic acid,n-tetradecyl ester
EINECS 204-000-3
n-Tetradecan-1-ol
Tetradecan-1-ol
2-Propenoicacid,tetradecylester
Kalcohl 4098
n-1-tetradecanol
Tetradecyl2-propenoate
Myristyl acrylate
TETRADECYL ACRYLATE
1-Hydroxytetradecane
Tetradecylacrylat
Q14
Kalcohl 40
XB8655000 [RTECS]
MFCD00004757

Biological Activity

[Description]:

1-Tetradecanol, isolated from Myristica fragrans, is a straight-chain saturated fatty alcohol. 1-Tetradecanol possesses antibacterial and anti-inflammatory (periodontitis) activity[1].

[Related Catalog]:

Research Areas >> Infection
Research Areas >> Inflammation/Immunology
Signaling Pathways >> Anti-infection >> Bacterial

[References]

[1]. XiaoyeGeng, et al. Design and fabrication of reversible thermochromic microencapsulated phase change materials for thermal energy storage and its antibacterial activity. Energy. Volume 159, 15 September 2018, Pages 857-869.

Chemical & Physical Properties

[ Density]:
0.8±0.1 g/cm3

[ Boiling Point ]:
263.2±0.0 °C at 760 mmHg

[ Melting Point ]:
35-39 °C(lit.)

[ Molecular Formula ]:
C14H30O

[ Molecular Weight ]:
214.387

[ Flash Point ]:
125.9±4.6 °C

[ Exact Mass ]:
214.229660

[ PSA ]:
20.23000

[ LogP ]:
6.19

[ Vapour density ]:
7.4 (vs air)

[ Vapour Pressure ]:
0.0±1.2 mmHg at 25°C

[ Index of Refraction ]:
1.445

[ Storage condition ]:
−20°C

[ Water Solubility ]:
insoluble

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
XB8655000
CHEMICAL NAME :
1-Tetradecanol
CAS REGISTRY NUMBER :
112-72-1
BEILSTEIN REFERENCE NO. :
1742652
LAST UPDATED :
199712
DATA ITEMS CITED :
8
MOLECULAR FORMULA :
C14-H30-O
MOLECULAR WEIGHT :
214.44
WISWESSER LINE NOTATION :
Q14

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Human
REFERENCE :
85DKA8 "Cutaneous Toxicity, Proceedings of the 3rd Conference, 1976," Drill, V.A., and P. Lazar, eds., New York, Academic Press, Inc. 1977 Volume(issue)/page/year: -,127,1977
TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration into the eye
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
AJOPAA American Journal of Ophthalmology. (Ophthalmic Pub. Co., 435 N. Michigan Ave., Suite 1415, Chicago, IL 60611) Series 3: V.1- 1918- Volume(issue)/page/year: 29,1363,1946 ** ACUTE TOXICITY DATA **
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>5 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 13,699,1975
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
>5 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 13,699,1975 ** TUMORIGENIC DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
12 gm/kg/24W-I
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Skin and Appendages - tumors Tumorigenic - tumors at site of application
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 9,70,1966 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83128 No. of Facilities: 336 (estimated) No. of Industries: 7 No. of Occupations: 16 No. of Employees: 22755 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83128 No. of Facilities: 136 (estimated) No. of Industries: 5 No. of Occupations: 20 No. of Employees: 4525 (estimated) No. of Female Employees: 1820 (estimated)

Safety Information

[ Symbol ]:

GHS07, GHS09

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H319-H410

[ Precautionary Statements ]:
P273-P305 + P351 + P338-P501

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant

[ Risk Phrases ]:
R38

[ Safety Phrases ]:
S24/25

[ RIDADR ]:
UN 3077 9 / PGIII

[ WGK Germany ]:
-

[ RTECS ]:
XB8655000

[ HS Code ]:
2905199090

Synthetic Route

Precursor & DownStream

Customs

[ HS Code ]: 2905199090

[ Summary ]:
2905199090. saturated monohydric alcohols. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%

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