(1S,3R)-ACPD

Names

[ CAS No. ]:
111900-32-4

[ Name ]:
(1S,3R)-ACPD

[Synonym ]:
CB 1712
t-ACPD
1-Aminocyclopentane-1S,3R-dicarboxylic acid
1S,3R-ACPD
1-Amino-1,3-dicarboxycyclopentane
trans-ACPD
MFCD00153760
cis-ACPD
trans-(1S,3R)-1-Amino-1,3-cyclopentanedicarboxylic acid
1-Amino-1,3-cyclopentanedicarboxylic acid

Biological Activity

[Description]:

(1S,3R)-ACPD is a mGluR agonist that can depolarize pyramidal cells[1].

[Related Catalog]:

Signaling Pathways >> GPCR/G Protein >> mGluR

Research Areas >> Neurological Disease

[References]

[1]. A E Bandrowski, et al. Metabotropic glutamate receptors modify ionotropic glutamate responses in neocortical pyramidal cells and interneurons. Exp Brain Res. 2001 Jan;136(1):25-40.

Chemical & Physical Properties

[ Density]:
1.452g/cm3

[ Boiling Point ]:
352.7ºC at 760mmHg

[ Molecular Formula ]:
C₇H₁₁NO₄

[ Molecular Weight ]:
173.16700

[ Flash Point ]:
167.1ºC

[ Exact Mass ]:
173.06900

[ PSA ]:
100.62000

[ LogP ]:
0.35350

[ Vapour Pressure ]:
6.39E-06mmHg at 25°C

[ Index of Refraction ]:
1.563

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: GY4060000

CHEMICAL NAME :: 1,3-Cyclopentanedicarboxylic acid, 1-amino-, (1S-cis)-

CAS REGISTRY NUMBER :: 111900-32-4

LAST UPDATED :: 199801

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C7-H11-N-O4

MOLECULAR WEIGHT :: 173.19

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 5,108,1960

Safety Information

[ Hazard Codes ]:
Xn: Harmful;

[ Risk Phrases ]:
R20/21/22

[ Safety Phrases ]:
26-36-36/37

Related Compounds

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