DTAB

Names

[ Name ]:
DTAB

[Synonym ]:
Dodecyl trimethyl ammonium bromide
Lauryltrimethylammonium Bromide
dodecyl trimethylammonium bromide
N,N,N-Trimethyldodecan-1-aminium bromide
n-Dodecyl trimethylammonium bromide
Dodecyltrimethylammonium bromide
N,N,N-Trimethyl-1-dodecanaminium bromide
1-Dodecanaminium, N,N,N-trimethyl-, bromide (1:1)
DTAB
MFCD00011767
dodecyl(trimethyl)ammonium bromide
Dodecyltrimethylammonium bromide (DTAB)
dodecyl(trimethyl)azanium,bromide
Laurtrimonium bromide
EINECS 214-290-3

Biological Activity

[Description]:

Dodecyltrimethylammonium bromide (DTAB) is a surfactant. Dodecyltrimethylammonium bromide interacts with DNA and changes the mechanical properties of DNA on binding and the specific binding parameters of the interaction[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. E F Silva, et al. Dodecyltrimethylammonium bromide surfactant effects on DNA: Unraveling the competition between electrostatic and hydrophobic interactions.

Chemical & Physical Properties

[ Melting Point ]:
246 °C (dec.)(lit.)

[ Molecular Formula ]:
C₁₅H₃₄BrN

[ Molecular Weight ]:
308.341

[ Flash Point ]:
246°C

[ Exact Mass ]:
307.187469

[ LogP ]:
1.61750

[ Water Solubility ]:
soluble

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: BQ3195000

CHEMICAL NAME :: Ammonium, dodecyltrimethyl-, bromide

CAS REGISTRY NUMBER :: 1119-94-4

LAST UPDATED :: 199710

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C15-H34-N.Br

MOLECULAR WEIGHT :: 308.41

WISWESSER LINE NOTATION :: 12K1&1&1 &E

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 6800 ug/kg

TOXIC EFFECTS :: Lungs, Thorax, or Respiration - other changes

REFERENCE :: APTOA6 Acta Pharmacologica et Toxicologica. (Copenhagen, Denmark) V.1-59, 1945-86. For publisher information, see PHTOEH Volume(issue)/page/year: 47,17,1980

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 5200 ug/kg

TOXIC EFFECTS :: Lungs, Thorax, or Respiration - other changes

REFERENCE :: APTOA6 Acta Pharmacologica et Toxicologica. (Copenhagen, Denmark) V.1-59, 1945-86. For publisher information, see PHTOEH Volume(issue)/page/year: 47,17,1980

Safety Information

[ Symbol ]:

GHS07, GHS09

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H315-H319-H335-H410

[ Precautionary Statements ]:
P261-P273-P305 + P351 + P338-P501

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn:Harmful

[ Risk Phrases ]:
R22;R36/37/38

[ Safety Phrases ]:
S26-S36-S37/39

[ RIDADR ]:
UN3077

[ WGK Germany ]:
3

[ RTECS ]:
BQ3195000

[ Packaging Group ]:
III

[ Hazard Class ]:
9

[ HS Code ]:
2923900090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2923900090

[ Summary ]:
2923900090 other quaternary ammonium salts and hydroxides。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

Articles

Probing competitive interactions in quaternary formulations.

J. Colloid. Interface Sci. 454 , 35-43, (2015)

The interaction of amphiphilic block copolymers of the poly(ethylene oxide)-poly(propylene oxide)-poly(ethylene oxide) (PEO-PPO-PEO) group with small molecule surfactants may be "tuned" by the presenc...

Salt effect on microscopic structure and stability of colloidal complex obtained from neutral/polyelectrolyte block copolymer and oppositely charged surfactant.

Colloids Surf. B Biointerfaces 99 , 127-35, (2012)

The salt effect on complex formation of poly(acrylamide)-block-poly(acrylic acid) (PAM-b-PAA) and dodecyltrimethylammonium bromide (DTAB) at different NaBr concentrations, C(NaBr), was investigated by...

Analysis of plasma nucleotides in rat by micellar electrokinetic capillary chromatography/electrospray ionization mass spectrometry.

Rapid Commun. Mass Spectrom. 26(12) , 1426-36, (2012)

The aim of this study was to establish a simultaneous quantitative analysis method of nine endogenous nucleotides in rat plasma using micellar electrokinetic capillary chromatography/electrospray ioni...

Related Compounds

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