5-(6)-Carboxy-2',7'-dichlorofluorescein
Names
[ CAS No. ]:
111843-78-8
[ Name ]:
5-(6)-Carboxy-2',7'-dichlorofluorescein
[Synonym ]:
5-(6)-CDCF [5(6)-Carboxy-2',7'-dichlorofluorescein]
Biological Activity
[Description]:
[Related Catalog]:
[References]
Chemical & Physical Properties
[ Density]:
1.86g/cm3
[ Boiling Point ]:
732.3ºC at 760mmHg
[ Melting Point ]:
250ºC
[ Molecular Formula ]:
C21H10Cl2O7
[ Molecular Weight ]:
445.20600
[ Flash Point ]:
396.7ºC
[ Exact Mass ]:
443.98000
[ PSA ]:
113.29000
[ LogP ]:
4.67080
[ Vapour Pressure ]:
0mmHg at 25°C
MSDS
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ RIDADR ]:
NONH for all modes of transport
Articles
Free Radic. Biol. Med. 37 , 1779-1789, (2004)
Mitochondrial dysfunction and oxidative stress occur in neurodegenerative diseases. Other results show that bombesin-releasable calcium stores (BRCS) from the endoplasmic reticulum (ER) are exaggerate...
Homocysteinic acid causes oxidative stress in lymphocytes by potentiating toxic effect of NMDA.Bull. Exp. Biol. Med. 140(1) , 33-7, (2005)
Short-term incubation of lymphocytes with homocysteine or its oxidation product homocysteinic acid increased the formation of reactive oxygen species and cell necrosis (in case of homocysteinic acid)....
Characterization of SAGE Mdr1a (P-gp), Bcrp, and Mrp2 knockout rats using loperamide, paclitaxel, sulfasalazine, and carboxydichlorofluorescein pharmacokinetics.Drug Metab. Dispos. 40 , 1825-33, (2012)
Transporter gene knockout rats are practically advantageous over murine models for pharmacokinetic and excretion studies, but their phenotypic characterization is lacking. At present, relevant aspects...