Trioctylamine

Names

[ Name ]:
Trioctylamine

[Synonym ]:
EINECS 214-242-1
MFCD00009560
Trioctylamine
Tri-n-octylamine
N,N-Dioctyloctan-1-amine
Tri-Normal-Octylamine
1-Octanamine, N,N-dioctyl-
N,N-Dioctyl-1-octanamine

Chemical & Physical Properties

[ Density]:
0.8±0.1 g/cm3

[ Boiling Point ]:
363.5±10.0 °C at 760 mmHg

[ Melting Point ]:
34 °C

[ Molecular Formula ]:
C₂₄H₅₁N

[ Molecular Weight ]:
353.668

[ Flash Point ]:
147.4±6.6 °C

[ Exact Mass ]:
353.402161

[ PSA ]:
3.24000

[ LogP ]:
11.22

[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.454

[ Water Solubility ]:
chloroform: 0.1 g/mL, clear, colorless

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: RG8225000

CHEMICAL NAME :: 1-Octanamine, N,N-dioctyl-

CAS REGISTRY NUMBER :: 1116-76-3

BEILSTEIN REFERENCE NO. :: 1210618

LAST UPDATED :: 199701

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C24-H51-N

MOLECULAR WEIGHT :: 353.76

WISWESSER LINE NOTATION :: 8N8&8

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: HYDRDA Hydrometallurgy. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1975- Volume(issue)/page/year: 3,201,1978

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 62500 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CBCCT* "Summary Tables of Biological Tests," National Research Council Chemical-Biological Coordination Center. (National Academy of Science Library, 2101 Constitution Ave., NW, Washington, DC 20418) Volume(issue)/page/year: 4,323,1952 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 84214 No. of Facilities: 35 (estimated) No. of Industries: 2 No. of Occupations: 2 No. of Employees: 63 (estimated)

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xi:Irritant;N:Dangerousfortheenvironment;

[ Risk Phrases ]:
R36/37/38;R51/53

[ Safety Phrases ]:
S26-S61-S36/37/39-S29

[ RIDADR ]:
UN3082

[ WGK Germany ]:
2

[ RTECS ]:
RG8225000

[ Packaging Group ]:
III

[ Hazard Class ]:
9

[ HS Code ]:
2921199090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2921199090

[ Summary ]:
2921199090 other acyclic monoamines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles

Label-Free Nanoplasmonic-Based Short Noncoding RNA Sensing at Attomolar Concentrations Allows for Quantitative and Highly Specific Assay of MicroRNA-10b in Biological Fluids and Circulating Exosomes.

ACS Nano 9 , 11075-89, (2015)

MicroRNAs are short noncoding RNAs consisting of 18-25 nucleotides that target specific mRNA moieties for translational repression or degradation, thereby modulating numerous biological processes. Alt...

Application of artificial neural network to investigate the effects of 5-fluorouracil on ribonucleotides and deoxyribonucleotides in HepG2 cells.

Sci. Rep. 5 , 16861, (2015)

Endogenous ribonucleotides and deoxyribonucleotides are essential metabolites that play important roles in a broad range of key cellular functions. Their intracellular levels could also reflect the ac...

Hollow fibre liquid phase micro-extraction by facilitated anionic exchange for the determination of flavonoids in faba beans (Vicia faba L.).

Phytochem. Anal. 26 , 346-52, (2015)

Flavonoids are polyphenolic compounds found ubiquitously in foods of plant origin. They are commonly extracted from plant materials with ethanol, methanol, water, their combination or even with acidif...