Azepane
Names
[ CAS No. ]:
111-49-9
[ Name ]:
Azepane
[Synonym ]:
Hexahydroazepine
Hexamethyleneimine
Perhydroazepine
Homopiperidine
1H-Azepine, hexahydro-
tetrahydroazepine
HEXAMETHYLENIMINE
Azacycloheptane
EINECS 203-875-9
Hexahydro-1H-azepine
Azepane
1H-Azepine,hexahydro
MFCD00006934
hexamethylene amine
3,4,5,6-Tetrahydroazepine
perhydro-1H-azepine
Chemical & Physical Properties
[ Density]:
0.8±0.1 g/cm3
[ Boiling Point ]:
142.7±8.0 °C at 760 mmHg
[ Melting Point ]:
-37°C
[ Molecular Formula ]:
C6H13N
[ Molecular Weight ]:
99.174
[ Flash Point ]:
18.3±0.0 °C
[ Exact Mass ]:
99.104797
[ PSA ]:
12.03000
[ LogP ]:
1.50
[ Vapour Pressure ]:
5.5±0.3 mmHg at 25°C
[ Index of Refraction ]:
1.429
[ Water Solubility ]:
soluble
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- CM3150000
- CHEMICAL NAME :
- 1H-Azepine, hexahydro-
- CAS REGISTRY NUMBER :
- 111-49-9
- BEILSTEIN REFERENCE NO. :
- 0001084
- LAST UPDATED :
- 199806
- DATA ITEMS CITED :
- 9
- MOLECULAR FORMULA :
- C6-H13-N
- MOLECULAR WEIGHT :
- 99.20
- WISWESSER LINE NOTATION :
- T7MTJ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 20700 ug/kg
- TOXIC EFFECTS :
- Behavioral - food intake (animal) Lungs, Thorax, or Respiration - pulmonary emboli Liver - other changes
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0534842
- TYPE OF TEST :
- LCLo - Lowest published lethal concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 33300 mg/m3/30M
- TOXIC EFFECTS :
- Lungs, Thorax, or Respiration - pulmonary emboli
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0534842
- TYPE OF TEST :
- LC50 - Lethal concentration, 50 percent kill
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 10800 mg/m3/2H
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982 Volume(issue)/page/year: -,74,1982
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 1260 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0539976
- TYPE OF TEST :
- LD - Lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- >50 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- TPKVAL Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. (Izdatel'stvo Meditsina, Moscow, USSR) No.1- 1961- Volume(issue)/page/year: 10,25,1968 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-RUSSIA:STEL 0.5 mg/m3;Skin JAN 1993
Safety Information
[ Hazard Codes ]:
F:Flammable;T+:Verytoxic;
[ Risk Phrases ]:
R11;R20;R28;R34
[ Safety Phrases ]:
S26-S36/37/39-S45-S28A-S16-S1
[ RIDADR ]:
UN 2493 3/PG 2
[ WGK Germany ]:
3
[ RTECS ]:
CM3150000
[ Packaging Group ]:
II
[ Hazard Class ]:
3
[ HS Code ]:
2933990090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2933990090
[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%