L-Tyrosine-13C

Names

[ Name ]:
L-Tyrosine-13C

[Synonym ]:
L-Tyrosine-C
L-(C)Tyrosine
L-4-Hydroxyphenylalanine-2-13C
L-Tyrosine-2-13C
L-Tyrosine-1-13C
MFCD00083988

Biological Activity

[Description]:

L-Tyrosine-13C is the 13C-labeled L-Tyrosine. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex.

[Related Catalog]:

Research Areas >> Neurological Disease

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Melting Point ]:
>300ºC (dec.)(lit.)

[ Molecular Formula ]:
C₈₁₃CH₁₁NO₃

[ Molecular Weight ]:
182.181

[ Exact Mass ]:
182.077255

[ PSA ]:
83.55000

[ LogP ]:
1.04690

[ Index of Refraction ]:
1.614

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
36/37/38

[ Safety Phrases ]:
26-36

[ RIDADR ]:
NONH for all modes of transport

Related Compounds

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