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L-Tyrosyl-L-isoleucylglycyl-L-seryl-L-argininamide

Names

[ CAS No. ]:
110590-65-3

[ Name ]:
L-Tyrosyl-L-isoleucylglycyl-L-seryl-L-argininamide

[Synonym ]:
LAMININ PENTAPEPTIDE YIGSR-NH2
YIGSR aMide
YIGSR-NH2
TYR-ILE-GLY-SER-ARG-NH2
LAMININ PENTAPEPTIDE YIGSR-NH2 2ACOH 2H2O
LAMININ PENTAPEPTIDE,AMIDE
TYR-ILE-GLY-SER-ARG-NH2 2ACOH 2H2O
L-Tyrosyl-L-isoleucylglycyl-L-seryl-L-argininamide
H-TYR-ILE-GLY-SER-ARG-NH2
Pentapeptide-2

Biological Activity

[Description]:

H-Tyr-Ile-Gly-Ser-Arg-NH2 is a hexapeptide that is an essential fragment of laminin responsible for efficient cell adhesion and receptor binding. H-Tyr-Ile-Gly-Ser-Arg-NH2 promotes various epithelial cell adhesion activities[1].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Others >> Others

[References]

[1]. Graf J, et al. A pentapeptide from the laminin B1 chain mediates cell adhesion and binds the 67,000 laminin receptor. Biochemistry. 1987 Nov 3;26(22):6896-900.  

Chemical & Physical Properties

[ Molecular Formula ]:
C26H43N9O7

[ Molecular Weight ]:
593.67600

[ Exact Mass ]:
593.32900

[ PSA ]:
287.87000

[ LogP ]:
0.77470

Related Compounds