tirilazad

Names

[ Name ]:
tirilazad

[Synonym ]:
[14C]-Tirilazad mesylate
Freedox
Tirilazad mesilate (JAN)
UNII-19B418DV39
Freedox (TN)
Tirilazad mesylate

Biological Activity

[Description]:

Tirilazad mesylate (U 74006F) is a nonglucocorticoid, 21-aminosteroid that inhibits lipid peroxidation. Tirilazad mesylate can attenuate brain or spinal cord injury caused by trauma, stroke, ischemia and reperfusion injury. Tirilazad mesylate has antiviral activities against nCoV. Tirilazad mesylate is neuroprotective for ischaemic stroke, can be used for subarachnoid hemorrhage research[1][2][3].

[Related Catalog]:

Research Areas >> Infection

Research Areas >> Neurological Disease

[References]

[1]. Bath PM, et al. Tirilazad for acute ischaemic stroke. Cochrane Database Syst Rev. 2001;(4):CD002087.

[2]. Zhang S, et al. Tirilazad for aneurysmal subarachnoid haemorrhage. Cochrane Database Syst Rev. 2010 Feb 17;(2):CD006778.

[3]. Tirilazad mesylate in acute ischemic stroke: A systematic review. Tirilazad International Steering Committee. Stroke. 2000 Sep;31(9):2257-65.

Chemical & Physical Properties

[ Boiling Point ]:
812.9ºC at 760 mmHg

[ Molecular Formula ]:
C₃₉H₅₆N₆O₅S

[ Molecular Weight ]:
720.96400

[ Flash Point ]:
445.4ºC

[ Exact Mass ]:
720.40300

[ PSA ]:
135.63000

[ LogP ]:
6.17600

[ Vapour Pressure ]:
1.71E-26mmHg at 25°C

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.