ASP3026

Names

[ Name ]:
ASP3026

[Synonym ]:
N2-[2-Methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]-N4-[2-[(1-methylethyl)sulfonyl]phenyl]-1,3,5-triazine-2,4-diamine
cc-325
QCR-144
N-{2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl}-N'-[2-(propane-2-sulfonyl)phenyl]-1,3,5-triazine-2,4-diamine
ASP 3026
N-[2-(isopropylsulfonyl)phenyl]-N'-{2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl}-1,3,5-triazine-2,4-diamine
1,3,5-Triazine-2,4-diamine, N-[2-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]-N-[2-[(1-methylethyl)sulfonyl]phenyl]-
CS-0787
UNII-HP4L6MXF10
N-[2-(Isopropylsulfonyl)phenyl]-N'-{2-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl}-1,3,5-triazine-2,4-diamine
ASP3026

Biological Activity

[Description]:

ASP3026 is a novel and selective inhibitor for ALK (anaplastic lymphoma kinase) with IC50 of 3.5 nM.

[Related Catalog]:

Signaling Pathways >> Protein Tyrosine Kinase/RTK >> ALK

Research Areas >> Cancer

[References]

[1]. Sadao Kuromitsu, et al. AACR 102nd Annual Meeting, 2011.

[Related Small Molecules]

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
794.3±70.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₉H₄₀N₈O₃S

[ Molecular Weight ]:
580.745

[ Flash Point ]:
434.2±35.7 °C

[ Exact Mass ]:
580.294434

[ PSA ]:
127.43000

[ LogP ]:
1.01

[ Vapour Pressure ]:
0.0±2.8 mmHg at 25°C

[ Index of Refraction ]:
1.620

[ Storage condition ]:
-20°C

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.