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m-PEG7-CH2COOH

Names

[ CAS No. ]:
1093647-41-6

[ Name ]:
m-PEG7-CH2COOH

[Synonym ]:
MFCD13184957
2,5,8,11,14,17,20,23-Octaoxahexacosan-26-oic acid

Biological Activity

[Description]:

m-PEG7-CH2COOH is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker

[Target]

Non-cleavable


[In Vitro]

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

[References]

[1]. Tinya Abrams, et al. Antibody drug conjugates. WO2016203432A1.

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
503.0±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C18H36O10

[ Molecular Weight ]:
412.472

[ Flash Point ]:
164.2±23.6 °C

[ Exact Mass ]:
412.230835

[ LogP ]:
-2.78

[ Vapour Pressure ]:
0.0±2.8 mmHg at 25°C

[ Index of Refraction ]:
1.456

Safety Information

[ Hazard Codes ]:
Xi


Related Compounds