HNGF6A

Names

[ Name ]:
HNGF6A

Biological Activity

[Description]:

HNGF6A is a humanin analogue. HNGF6A increases glucose-stimulated insulin secretion and glucose metabolism, and has the potential for diabetes research. HNGF6A inhibits of ROS production during oxidative stress. HNGF6A can prevent endothelial dysfunction and atherosclerosis in vivo[1][2].

[Related Catalog]:

Research Areas >> Cardiovascular Disease

Research Areas >> Metabolic Disease

Research Areas >> Neurological Disease

[References]

[1]. Yun K Oh, et al. Humanin preserves endothelial function and prevents atherosclerotic plaque progression in hypercholesterolemic ApoE deficient mice. Atherosclerosis. 2011 Nov;219(1):65-73.

[2]. Regina Kuliawat, et al. Potent humanin analog increases glucose-stimulated insulin secretion through enhanced metabolism in the β cell. FASEB J. 2013 Dec;27(12):4890-8.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₁₂H₁₉₈N₃₄O₃₁S₂

[ Molecular Weight ]:
2581.11

Related Compounds

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