PP121
Names
[ CAS No. ]:
1092788-83-4
[ Name ]:
PP121
[Synonym ]:
S2622_Selleck
PP-121,PP 121
1-cyclopentyl-3-(1H-pyrrolo[2,3-b]pyridin-5-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
KS1
PP121
Biological Activity
[Description]:
[Related Catalog]:
[Target]
mTOR:10 nM (IC50)
PDGFR:2 nM (IC50)
VEGFR2:12 nM (IC50)
Src:14 nM (IC50)
DNK-PK:60 nM (IC50)
[In Vitro]
[In Vivo]
[Kinase Assay]
[Cell Assay]
[Animal admin]
[References]
[Related Small Molecules]
Chemical & Physical Properties
[ Density]:
1.63
[ Boiling Point ]:
650.9±50.0 °C at 760 mmHg
[ Molecular Formula ]:
C17H17N7
[ Molecular Weight ]:
319.364
[ Flash Point ]:
347.4±30.1 °C
[ Exact Mass ]:
319.154541
[ PSA ]:
98.30000
[ LogP ]:
2.41
[ Appearance of Characters ]:
off-white
[ Vapour Pressure ]:
0.0±1.9 mmHg at 25°C
[ Index of Refraction ]:
1.881
[ Storage condition ]:
Store at +4°C
[ Water Solubility ]:
DMSO: >10mg/mL
MSDS
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H302
[ Hazard Codes ]:
Xn
[ Risk Phrases ]:
22
[ RIDADR ]:
UN 2811 6.1 / PGIII
[ Hazard Class ]:
22