(3S,4S)-Tofacitinib

Names

[ Name ]:
(3S,4S)-Tofacitinib

[Synonym ]:
(3S,4S)-Tofacitinib
3-((3S,4S)-3-((1H-Indol-4-yl)(methyl)amino)-4-methylpiperidin-1-yl)-3-oxopropan-enitrile
3-((3S,4S)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile
CS-1108

Biological Activity

[Description]:

(3S,4S)-Tofacitinib is the S-enantiomer of Tofacitinib. Tofacitinib inhibits JAK3 with IC50 of 1 nM.

[Related Catalog]:

Research Areas >> Inflammation/Immunology

[Related Small Molecules]

Baricitinib | Upadacitinib | Pacritinib | CYT387 | AZD1480 | Fedratinib(SAR302503,TG101348) | WP1066 | CHZ868 | AT9283 | GLPG0634 | Itacitinib | cerdulatinib | LY2784544 | SB1317 | Peficitinib

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₆H₂₀N₆O

[ Molecular Weight ]:
312.37000

[ Exact Mass ]:
312.17000

[ PSA ]:
88.91000

[ LogP ]:
1.48268

[ Storage condition ]:
-20°C

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.