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Camellianin A

Names

[ CAS No. ]:
109232-77-1

[ Name ]:
Camellianin A

[Synonym ]:
Camellianin A

Biological Activity

[Description]:

Camellianin A, the main flavonoid in A. nitida leaves, displays anticancer activity and angiotensin converting enzyme (ACE)-inhibitory activity. Camellianin A inhibits the proliferation of the human Hep G2 and MCF-7 cell lines and induces the significant increase of the G0/G1 cell population[1][2].

[Related Catalog]:

Signaling Pathways >> Apoptosis >> Apoptosis
Research Areas >> Cancer

[References]

[1]. Gao H, et al. Anti-proliferative effect of camellianin A in Adinandra nitida leaves and its apoptotic induction in human Hep G2 and MCF-7 cells. Molecules. 2010 May 28;15(6):3878-86.

[2]. Liu B, et al. Antioxidant and angiotensin converting enzyme (ACE) inhibitory activities of ethanol extract and pure flavonoids from Adinandra nitida leaves. Pharm Biol. 2010 Dec;48(12):1432-8.

Chemical & Physical Properties

[ Density]:
1.64g/cm3

[ Boiling Point ]:
923ºC at 760 mmHg

[ Molecular Formula ]:
C29H32O15

[ Molecular Weight ]:
620.55500

[ Flash Point ]:
302.1ºC

[ Exact Mass ]:
620.17400

[ PSA ]:
235.04000

[ Vapour Pressure ]:
0mmHg at 25°C

[ Index of Refraction ]:
1.692

[ Water Solubility ]:
Very slightly soluble (0.12 g/L) (25 ºC)

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds