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camellianin B

Names

[ CAS No. ]:
109232-76-0

[ Name ]:
camellianin B

[Synonym ]:
Camellianin B

Biological Activity

[Description]:

Camellianin B, a flavonoid compound, is a Camellianin A metabolite. Camellianin B has antioxidant and angiotensin converting enzyme (ACE) inhibitory activities[1][2].

[Related Catalog]:

Signaling Pathways >> Metabolic Enzyme/Protease >> Angiotensin-converting Enzyme (ACE)
Research Areas >> Metabolic Disease

[In Vitro]

At 500 μg/mL, the ACE inhibitory activities of Camellianin B is 40.68%. Camellianin B has DPPH radical scavenging activity with IC50 value of 1.8 mg/mL[2].

[In Vivo]

Camellianin B has a wide tissue distribution with brain penetration[1].

[References]

[1]. Yunliang Zheng, et al. Pharmacokinetics and tissue distribution study of camellianin A and its major metabolite in rats by liquid chromatography with tandem mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 2015 Aug 1;997:200-9.

[2]. Benguo Liu, et al. Antioxidant and angiotensin converting enzyme (ACE) inhibitory activities of ethanol extract and pure flavonoids from Adinandra nitida leaves. Pharm Biol. 2010 Dec;48(12):1432-8.

Chemical & Physical Properties

[ Density]:
1.69g/cm3

[ Boiling Point ]:
937.4ºC at 760mmHg

[ Molecular Formula ]:
C27H30O14

[ Molecular Weight ]:
578.51900

[ Flash Point ]:
312.4ºC

[ Exact Mass ]:
578.16400

[ PSA ]:
228.97000

[ Vapour Pressure ]:
0mmHg at 25°C

[ Index of Refraction ]:
1.726

Related Compounds