4-(4-Nitrobenzyl)pyridine
Names
[ CAS No. ]:
1083-48-3
[ Name ]:
4-(4-Nitrobenzyl)pyridine
[Synonym ]:
4-(4-Nitrobenzyl)pyridine
Pyridine, 4-[(4-nitrophenyl)methyl]-
4-(4-Nitro-benzyl)-pyridine
4-[(4-nitrophenyl)methyl]pyridine
EINECS 214-108-2
4-(p-Nitrobenzyl)pyridine
Pyridine, 4- (p-nitrobenzyl)-
MFCD00006445
Chemical & Physical Properties
[ Density]:
1.2±0.1 g/cm3
[ Boiling Point ]:
383.4±22.0 °C at 760 mmHg
[ Melting Point ]:
69-71 °C(lit.)
[ Molecular Formula ]:
C12H10N2O2
[ Molecular Weight ]:
214.220
[ Flash Point ]:
185.6±22.3 °C
[ Exact Mass ]:
214.074234
[ PSA ]:
58.71000
[ LogP ]:
2.44
[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C
[ Index of Refraction ]:
1.609
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UT6360000
- CHEMICAL NAME :
- Pyridine, 4-(p-nitrobenzyl)-
- CAS REGISTRY NUMBER :
- 1083-48-3
- BEILSTEIN REFERENCE NO. :
- 0170877
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C12-H10-N2-O2
- MOLECULAR WEIGHT :
- 214.24
- WISWESSER LINE NOTATION :
- T6NJ D1R DNW
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 89 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#12116 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - E0062 No. of Facilities: 8 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 86 (estimated) No. of Female Employees: 78 (estimated)
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xi:Irritant;
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
S26-S36
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
UT6360000
[ HS Code ]:
29333999
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2933399090
[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
Articles
Biotechnol. Lett. 27(23-24) , 1921-7, (2005)
Focusing on directed evolution to tailor enzymes as usable biocatalysts for fine chemistry, we have studied in detail several colorimetric assays for quantitative analysis of epoxide hydrolase (EH) ac...
2,4-dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one (DIMBOA) inhibits trichothecene production by Fusarium graminearum through suppression of Tri6 expression.Int. J. Food Microbiol. 214 , 123-8, (2015)
Fusarium head blight (FHB) is a devastating disease of wheat (Triticum aestivum L.) caused by a mycotoxigenic fungus Fusarium graminearum resulting in significantly decreased yields and accumulation o...
The relationship between reactivity of metabolites of pyrrolizidine alkaloids and extrahepatic toxicity.Proc. West. Pharmacol. Soc. 42 , 13-6, (1999)
Pyrrolizidine alkaloids (PAs) are a large group of structurally similar toxins. In animals, including man, they are hepatotoxic and in some cases pneumo- and neurotoxic. PAs are metabolized by the liv...