1,2-butanediol
Names
[ CAS No. ]:
584-03-2
[ Name ]:
1,2-butanediol
[Synonym ]:
1,2-Dihydroxybutane
EINECS 209-527-2
Butanediol, 1,2-
1,2-(Dihydroxy)butane
MFCD00004570
±-1,2-Butanediol
1,2-butanediol
1,2-butylene glycol
1,2-Butanediol, (±)-
butane-1,2-diol
methylpropyldiol
UNII:RUN0H01QEU
Chemical & Physical Properties
[ Density]:
1.0±0.1 g/cm3
[ Boiling Point ]:
190.3±8.0 °C at 760 mmHg
[ Melting Point ]:
-50 °C
[ Molecular Formula ]:
C4H10O2
[ Molecular Weight ]:
90.121
[ Flash Point ]:
93.3±0.0 °C
[ Exact Mass ]:
90.068077
[ PSA ]:
40.46000
[ LogP ]:
-0.81
[ Vapour Pressure ]:
0.1±0.8 mmHg at 25°C
[ Index of Refraction ]:
1.438
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- EK0380000
- CHEMICAL NAME :
- 1,2-Butanediol
- CAS REGISTRY NUMBER :
- 584-03-2
- BEILSTEIN REFERENCE NO. :
- 0969169
- LAST UPDATED :
- 199709
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C4-H10-O2
- MOLECULAR WEIGHT :
- 90.14
- WISWESSER LINE NOTATION :
- QY2&1Q
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 16 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,207,1986
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 4192 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 49,385,1979 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X7923 No. of Facilities: 7 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 1822 (estimated) No. of Female Employees: 272 (estimated)
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;half-mask respirator (US);multi-purpose combination respirator cartridge (US)
[ Hazard Codes ]:
Xi
[ Safety Phrases ]:
S24/25
[ WGK Germany ]:
2
[ RTECS ]:
EK0380000
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Articles
J. Anal. Toxicol. 38(9) , 676-80, (2014)
A liquid chromatography coupled with electrospray tandem mass spectrometry method was developed for the analysis of ethylene glycol, diethylene glycol, triethylene glycol, 1,4-butanediol, 1,2-butanedi...
Efficient conversion of 1,2-butanediol to (R)-2-hydroxybutyric acid using whole cells of Gluconobacter oxydans.Bioresour. Technol. 115 , 75-8, (2012)
(R)-2-Hydroxybutyric acid ((R)-2-HBA) is an important building block for azinothricin family of antitumour antibiotics and biodegradable poly(2-hydroxybutyric acid). However, optically active (R)-2-HB...
Simultaneous extraction of flavonoids from Chamaecyparis obtusa using deep eutectic solvents as additives of conventional extractions solvents.J. Chromatogr. Sci. 53 , 836-40, (2015)
Three flavones (quercetin, myricetin and amentoflavone) were extracted from Chamaecyparis obtusa leaves using deep eutectic solvents (DESs) as additives to conventional extractions solvents. Sixteen D...