FUMAGILLOL

Names

[ Name ]:
FUMAGILLOL

[Synonym ]:
Fumagillol

Biological Activity

[Description]:

Fumagillol is a direct precursor of fumagillin. Fumagillin, as an antimicrobial agent, is a potent and selective inhibitor of angiogenesis[1].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Bacterial

[In Vitro]

Fumagillol derivatives have no significant cytotoxic effect on CHO cells[1].

[References]

[1]. Bedel, O., et al. "Syntheses of antiangiogenic or cytotoxic natural products: Fumagillin and bengacarboline" Pure and Applied Chemistry, vol. 77, no. 7, 2005, pp. 1139-1152.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₆H₂₆O₄

[ Molecular Weight ]:
282.37500

[ Exact Mass ]:
282.18300

[ PSA ]:
54.52000

[ LogP ]:
2.05510

[ Vapour Pressure ]:
1.08E-07mmHg at 25°C

Related Compounds

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