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isoCA-4

Names

[ CAS No. ]:
1067880-31-2

[ Name ]:
isoCA-4

Biological Activity

[Description]:

isoCA-4, a Combretastatin A4 derivative, is a tubulin polymerization inhibitor. isoCA-4 has anti-proliferative activities[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Cell Cycle/DNA Damage >> Microtubule/Tubulin
Signaling Pathways >> Cytoskeleton >> Microtubule/Tubulin

[References]

[1]. Xiang-Yu Yan, et al. Design, synthesis, and biological evaluation of novel diphenylamine derivatives as tubulin polymerization inhibitors targeting the colchicine binding site. Eur J Med Chem. 2022 Apr 16;237:114372.

Chemical & Physical Properties

[ Molecular Formula ]:
C18H20O5

[ Molecular Weight ]:
316.35

Related Compounds