Citronellal

Names

[ CAS No. ]:
106-23-0

[ Name ]:
Citronellal

[Synonym ]:
Citronellal
3,7-dimethyloct-6-en-1-al
CITRONELLAL 80
Citronellel
d-rhodinal
β-Citronellal
ALPHA-CITRONELLAL
6-Octenal, 3,7-dimethyl-
RHODINAL
3,7-dimethyloct-6-enal
3,7-Dimethyl-6-octenal
b-Citronellal
UNII:QB99VZZ7GZ
(±)-3,7-Dimethyl-6-octenal
EINECS 203-376-6
Levo-citronellal
dl-Citronellal
(±)-citronellal
MFCD00038090
Citronella

Biological Activity

[Description]:

Citronellal is a monoterpenea from the essential oils in various aromatic species of plants, with depressant, hypnotic, and antinociceptive properties. Citronellal attenuates mechanical nociception, mediated in part by the NO-cGMP-ATP-sensitive K⁺ channel pathway[1][2].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Neurological Disease

[References]

[1]. Melo MS, et al. Antinociceptive effect of citronellal in mice. Pharm Biol. 2010 Apr;48(4):411-6.

[2]. de Santana MT, et al. Citronellal, a monoterpene present in Java citronella oil, attenuates mechanical nociception response in mice. Pharm Biol. 2013 Sep;51(9):1144-9.

Chemical & Physical Properties

[ Density]:
0.8±0.1 g/cm3

[ Boiling Point ]:
208.4±9.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₀H₁₈O

[ Molecular Weight ]:
154.249

[ Flash Point ]:
75.6±0.0 °C

[ Exact Mass ]:
154.135757

[ PSA ]:
17.07000

[ LogP ]:
3.48

[ Vapour Pressure ]:
0.2±0.4 mmHg at 25°C

[ Index of Refraction ]:
1.437

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07, GHS09

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H317-H319-H335-H411

[ Precautionary Statements ]:
P273-P280-P333 + P313-P337 + P313-P391

[ Personal Protective Equipment ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S36/37-S61-S37/39-S26-S36

[ RIDADR ]:
UN 3082 9/PG 3

[ WGK Germany ]:
3

[ RTECS ]:
RH2140000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Articles

Circuit formation and function in the olfactory bulb of mice with reduced spontaneous afferent activity.

J. Neurosci. 35(1) , 146-60, (2015)

The type of neuronal activity required for circuit development is a matter of significant debate. We addressed this issue by analyzing the topographic organization of the olfactory bulb in transgenic ...

The Mosquito Repellent Citronellal Directly Potentiates Drosophila TRPA1, Facilitating Feeding Suppression.

Mol. Cells 38 , 911-7, (2015)

Citronellal, a well-known plant-derived mosquito repellent, was previously reported to repel Drosophila melanogaster via olfactory pathways involving but not directly activating Transient Receptor Pot...

Electrophysiological and behavioral characterization of bioactive compounds of the Thymus vulgaris, Cymbopogon winterianus, Cuminum cyminum and Cinnamomum zeylanicum essential oils against Anopheles gambiae and prospects for their use as bednet treatments.

Parasit. Vectors 8 , 316, (2015)

Laboratory and field studies showed that repellent, irritant and toxic actions of common public health insecticides reduce human-vector contact and thereby interrupt disease transmission. One of the m...

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.