m-PEG4-CH2-aldehyde

Names

[ CAS No. ]:
1059189-65-9

[ Name ]:
m-PEG4-CH2-aldehyde

[Synonym ]:
MFCD30458023

Biological Activity

[Description]:

m-PEG4-CH2-aldehyde is a PEG-based based PROTAC linker can be used in the synthesis of PROTACs.

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> PROTAC >> PROTAC Linker

[Target]

PEGs

[In Vitro]

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

[References]

[1]. Jennifer Riggs-Sauthier, et al. Oligomer-protease inhibitor conjugates. WO2008112289A2.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₁H₂₂O₆

[ Molecular Weight ]:
250.29

Safety Information

[ Hazard Codes ]:
Xi

m-PEG4-CH2-aldehyde

Names

Biological Activity

Chemical & Physical Properties

Safety Information

Related Compounds