m-PEG4-CH2-acid

Names

[ CAS No. ]:
874208-84-1

[ Name ]:
m-PEG4-CH2-acid

Biological Activity

[Description]:

m-PEG4-CH2-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> PROTAC >> PROTAC Linker

[Target]

PEGs

[In Vitro]

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

[References]

[1]. Zuluaga MF, et al. Enhanced prostate cancer targeting by modified protease sensitive photosensitizer prodrugs. Mol Pharm. 2012 Jun 4;9(6):1570-9.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₁H₂₂O₆

[ Molecular Weight ]:
250.29

[ Storage condition ]:
2-8°C

m-PEG4-CH2-acid

Names

Biological Activity

Chemical & Physical Properties

Related Compounds