SU 5614
Names
[ CAS No. ]:
1055412-47-9
[ Name ]:
SU 5614
[Synonym ]:
5-Chloro-3-[(3,5-dimethylpyrrol-2-yl)methylene]-2-indolinone
1H-Indole-2-carboxylic acid,5-chloro-3-[(3,5-dimethylphenyl)sulfonyl]
5-chloro-3-(3,5-dimethylphenyl-sulfonyl)indole-2-carboxylic acid
5-chloro-3-(3,5-dimethyl-1H-pyrrol-2-yl-methylene)-1,3-dihydro-indol-2-one
5-chloro-3-[(3,5-dimethylphenyl)sulfonyl]-1H-indole-2-carboxylic acid
3-[(3,5-dimethylphenyl)sulfonyl]-1H-indole-2-carboxylic acid
SU 5614
SU5614
Biological Activity
[Description]:
[Related Catalog]:
[References]
Chemical & Physical Properties
[ Molecular Formula ]:
C15H13ClN2O
[ Molecular Weight ]:
272.73000
[ Exact Mass ]:
272.07200
[ PSA ]:
48.38000
[ LogP ]:
3.86270
Safety Information
[ Hazard Statements ]:
H413
[ RIDADR ]:
NONH for all modes of transport
[ HS Code ]:
2933990090
Customs
[ HS Code ]: 2933990090
[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
Articles
Oncotarget 6 , 38804-15, (2015)
Internal tandem duplications within the juxtamembrane region of the FMS-like tyrosine kinase receptor FLT3 (FLT3-ITD) represents one of the most common mutations in patients with acute myeloid leukemi...
VEGF-A/NRP1 stimulates GIPC1 and Syx complex formation to promote RhoA activation and proliferation in skin cancer cells.Biol. Open 4 , 1063-76, (2015)
Neuropilin-1 (NRP1) has been identified as a VEGF-A receptor. DJM-1, a human skin cancer cell line, expresses endogenous VEGF-A and NRP1. In the present study, the RNA interference of VEGF-A or NRP1 s...