2-Acetamido-1,2-dideoxynojirimycin

Names

[ Name ]:
2-Acetamido-1,2-dideoxynojirimycin

[Synonym ]:
5-acetamido-1,3,4-thiadiazole
2-acetamido-1,5-imino-1,2,5-trideoxy-D-glucitol
Acetamide,N-1,3,4-thiadiazol-2-yl
2-acetamido-1,2,5-trideoxy-1,5-imino-D-glucitol
2-acetylamino-1,3,4-thiadiazole
1,3,4-Thiadiazole,2-acetamido
X 134
1,2-dideoxy-2-acetamidonojirimycin
N-Acetyl-2-amino-1,3,4-thiadiazol
2-acetamido-1,2-dideoxynojirimycin

Chemical & Physical Properties

[ Density]:
1.35 g/cm3

[ Boiling Point ]:
502.5ºC at 760 mmHg

[ Molecular Formula ]:
C₈H₁₆N₂O₄

[ Molecular Weight ]:
204.22400

[ Flash Point ]:
257.7ºC

[ Exact Mass ]:
204.11100

[ PSA ]:
101.82000

[ Vapour Pressure ]:
3.33E-12mmHg at 25°C

[ Index of Refraction ]:
1.565

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
26-36

[ RIDADR ]:
NONH for all modes of transport

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Articles

Bovine N-acetyl-beta-D-glucosaminidase: affinity purification and characterization of its active site with nitrogen containing analogs of N-acetylglucosamine.

Biochim. Biophys. Acta 1080 , 89-95, (1991)

Two N-acetylglucosaminidases were isolated from bovine kidney with a three step procedure featuring affinity purification on 2-acetamido-1,2,5-trideoxy-1,5-iminoglucitol (2-acetamido-1,2-dideoxynojiri...

Suppression of beta-N-acetylglucosaminidase in the N-glycosylation pathway for complex glycoprotein formation in Drosophila S2 cells.

Glycobiology 19 , 301-308, (2009)

Most insect cells have a simple N-glycosylation process and consequently paucimannosidic or simple core glycans predominate. Previously, we have shown that paucimannosidic N-glycan structures are domi...

Purification and characterization of recombinant human alpha-N-acetylglucosaminidase secreted by Chinese hamster ovary cells.

Protein Expr. Purif. 19 , 202-211, (2000)

alpha-N-Acetylglucosaminidase (EC 3.2.1.50) is a lysosomal enzyme that is deficient in the genetic disorder Sanfilippo syndrome type B. To study the human enzyme, we expressed its cDNA in Lec1 mutant ...