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Mytoxin B

Names

[ CAS No. ]:
105049-15-8

[ Name ]:
Mytoxin B

Biological Activity

[Description]:

Mytoxin B is an ADC cytotoxin. Mytoxin B is a satratoxin-type trichothecene macrolide and is similar to the effect of LY294002 (HY-10108). Mytoxin B induces cell apoptosis via PI3K/Akt pathway[1].

[Related Catalog]:

Signaling Pathways >> Apoptosis >> Apoptosis
Research Areas >> Cancer
Signaling Pathways >> Antibody-drug Conjugate >> ADC Cytotoxin
Signaling Pathways >> PI3K/Akt/mTOR >> PI3K

[References]

[1]. Huiliang Song, et al. Mytoxin B and Myrothecine A Induce Apoptosis in Human Hepatocarcinoma Cell Line SMMC-7721 via PI3K/Akt Signaling Pathway. Molecules. 2019 Jun 20;24(12):2291.

Chemical & Physical Properties

[ Molecular Formula ]:
C29H36O9

[ Molecular Weight ]:
528.59100

[ Exact Mass ]:
528.23600

[ PSA ]:
120.89000

[ LogP ]:
2.49970


Related Compounds

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