3alpha-akebonoic acid

Names

[ Name ]:
3alpha-akebonoic acid

[Synonym ]:
4a(2H)-Picenecarboxylic acid, 1,3,4,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-octadecahydro-10-hydroxy-6a,6b,9,9,12a-pentamethyl-2-methylene-, (4aS,6aS,6bR,8aR,10R,12aR,12bR,14bS)-
(4aS,6aS,6bR,8aR,10R,12aR,12bR,14bS)-10-Hydroxy-6a,6b,9,9,12a-pentamethyl-2-methylene-1,3,4,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-octadecahydro-4a(2H)-picenecarboxylic acid

Biological Activity

[Description]:

3α-Akebonoic acid is a α-glucosidase inhibitor with an IC50 value of 0.035 mM. 3α-Akebonoic acid shows antibacterial activity and cytotoxicity[1].

[Related Catalog]:

Research Areas >> Infection

Research Areas >> Metabolic Disease

Signaling Pathways >> Anti-infection >> Bacterial

[References]

[1]. Wang J, et al. Bioactive 30-noroleanane triterpenes from the pericarps of Akebia trifoliata. Molecules. 2014 Apr 4;19(4):4301-12.

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
556.6±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₉H₄₄O₃

[ Molecular Weight ]:
440.66

[ Flash Point ]:
304.5±26.6 °C

[ Exact Mass ]:
440.329041

[ PSA ]:
57.53000

[ LogP ]:
8.32

[ Vapour Pressure ]:
0.0±3.4 mmHg at 25°C

[ Index of Refraction ]:
1.567

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.