Tetrahydroxysqualene

Names

[ Name ]:
Tetrahydroxysqualene

[Synonym ]:
1,1,1,3-Propanetetrol, 2-[(4E,8E,12E,16Z)-4,8,13,17,21-pentamethyl-4,8,12,16,20-docosapentaen-1-ylidene]-, (2E)-
(6E,10E,14E,18E)-2,23-Bis(hydroxymethyl)-6,10,15,19-tetramethyl-2,6,10,14,18,22-tetracosahexaene-1,24-diol
2,6,10,14,18,22-Tetracosahexaene-1,24-diol, 2,23-bis(hydroxymethyl)-6,10,15,19-tetramethyl-, (6E,10E,14E,18E)-
(2E)-2-[(4E,8E,12E,16Z)-4,8,13,17,21-Pentamethyl-4,8,12,16,20-docosapentaen-1-ylidene]-1,1,1,3-propanetetrol

Biological Activity

[Description]:

Tetrahydroxysqualene is a triterpene, possessing antimycobacterial activity against Mycobacterium tuberculosis with an MIC of 10.0 μg/mL. Tetrahydroxysqualene can be isolated from the methanolic extracts of Rhus taitensis Guill[1].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Bacterial

[Target]

MIC: 10.0 μg/mL (Mycobacterium tuberculosis)[1]

[References]

[1]. Noro JC, et al. Tetrahdroxysqualene from Rhus taitensis shows antimycobacterial activity against Mycobacterium tuberculosis. J Nat Prod. 2008 Sep;71(9):1623-4.

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
620.9±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C₃₀H₅₀O₄

[ Molecular Weight ]:
474.716

[ Flash Point ]:
250.3±24.7 °C

[ Exact Mass ]:
474.370911

[ PSA ]:
80.92000

[ LogP ]:
9.67

[ Vapour Pressure ]:
0.0±4.1 mmHg at 25°C

[ Index of Refraction ]:
1.530

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds

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