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11(α)-methoxysaikosaponin F

Names

[ CAS No. ]:
104109-37-7

[ Name ]:
11(α)-methoxysaikosaponin F

[Synonym ]:
MFCD30725472

Biological Activity

[Description]:

11(α)-Methoxysaikosaponin F is a triterpenoid saponin isolated from Bupleurum marginatum Wall.ex DC(ZYCH) which is a promising therapeutic for liver fibrosis. 11(α)-Methoxysaikosaponin F has an IC50 of 387.7 nM with viability of hepatic stellate cells-T6 (HSCs-T6). Triterpenoid saponins have numerous targets, important network positions, and strong inhibitory activity[1].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Others >> Others

[References]

[1]. Liu X, et al. Bupleurum marginatum Wall.ex DC in Liver Fibrosis: Pharmacological Evaluation, Differential Proteomics, and Network Pharmacology. Front Pharmacol. 2018 May 17;9:524.

Chemical & Physical Properties

[ Density]:
1.38±0.1 g/cm3(Predicted)

[ Boiling Point ]:
1007.2±65.0 °C(Predicted)

[ Molecular Formula ]:
C49H82O18

[ Molecular Weight ]:
959.16

Related Compounds