7-Hydroxy-TSU-68

Names

[ CAS No. ]:
1035154-52-9

[ Name ]:
7-Hydroxy-TSU-68

Biological Activity

[Description]:

7-Hydroxy-TSU-68 is a derivative of TSU-68 (HY-10517). It is a metabolite of the biotransformation pathway of TSU-68 in human liver microsomes. The content represents the self-induced hydroxylation level of TSU-68[1].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Others >> Others

[References]

[1]. Ryuichi Kitamura, et al. Identification of human liver cytochrome P450 isoforms involved in autoinduced metabolism of the antiangiogenic agent (Z)-5-[(1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-propanoic acid (TSU-68). Drug Metab Dispos. 2008 Jun;36(6):1003-9.   

Chemical & Physical Properties

[ Molecular Formula ]:
C18H18N2O4

[ Molecular Weight ]:
326.35

Related Compounds

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