2'-Deoxycytidine-5'-monophosphoric acid

Names

[ Name ]:
2'-Deoxycytidine-5'-monophosphoric acid

[Synonym ]:
2'-Deoxycytidine 5'-monophosphate
2(1H)-pyrimidinone, 4-amino-1-(2-deoxy-5-O-phosphono-β-D-glycero-pentofuranosyl)-
[(2R,3S,5R)-5-(4-Amino-2-oxo-1(2H)-pyrimidinyl)-3-hydroxytetrahydro-2-furanyl]methyl dihydrogen phosphate
Deoxycytidylic acid
2′-Deoxycytidine 5′-monophosphate
2-pyrimidinol, 1-(2-deoxy-5-O-phosphono-β-D-erythro-pentofuranosyl)-1,4-dihydro-4-imino-
Deoxycytidine-5'-monophosphoric acid
Deoxycytidylic Acid Hydrate
5'-Cytidylic acid, 2'-deoxy-
dCMP
2'-Deoxycytidylic acid
2'-Deoxycytidine-5'-monophosphoric acid
2-Deoxycytidine-5'-monophosphoric acid
Deoxycytidine monophosphate
2'-Deoxy-5'-cytidylic acid
deoxycytidine 5'-phosphate
2'-Deoxycytidine 5'-Monophosphate Hydrate
MFCD00006546
EINECS 213-849-9
4-Amino-1-(2-deoxy-5-O-phosphono-β-D-glycero-pentofuranosyl)pyrimidin-2(1H)-one

Chemical & Physical Properties

[ Density]:
2.0±0.1 g/cm3

[ Boiling Point ]:
633.8±65.0 °C at 760 mmHg

[ Melting Point ]:
169-172 °C (dec.)

[ Molecular Formula ]:
C₉H₁₄N₃O₇P

[ Molecular Weight ]:
307.197

[ Flash Point ]:
337.1±34.3 °C

[ Exact Mass ]:
307.056946

[ PSA ]:
166.94000

[ LogP ]:
-2.17

[ Vapour Pressure ]:
0.0±4.2 mmHg at 25°C

[ Index of Refraction ]:
1.743

[ Storage condition ]:
2-8°C

[ Water Solubility ]:
H2O: 10 mg/mL, clear, colorless

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xn,Xi

[ Risk Phrases ]:
R20/21/22

[ Safety Phrases ]:
S22-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2934999090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Development of an electrochemical surface-enhanced Raman spectroscopy (EC-SERS) aptasensor for direct detection of DNA hybridization.

Phys. Chem. Chem. Phys. 17 , 21356-63, (2015)

Rapid detection of disease biomarkers at the patient point-of-care is essential to timely and effective treatment. The research described herein focuses on the development of an electrochemical surfac...

Metal free columns for determination of deoxynucleotide monophosphate by liquid chromatography/mass spectrometry and application to oligonucleotide.

J. Chromatogr. A. 1406 , 210-4, (2015)

We have developed a highly sensitive method for the analysis of deoxynucleotide monophosphates (dNMPs), which involves the use of liquid chromatography/mass spectrometry (LC/MS) and a new metal-free c...

The mechanism of action of beta-D-2'-deoxy-2'-fluoro-2'-C-methylcytidine involves a second metabolic pathway leading to beta-D-2'-deoxy-2'-fluoro-2'-C-methyluridine 5'-triphosphate, a potent inhibitor of the hepatitis C virus RNA-dependent RNA polymerase.

Antimicrob. Agents Chemother. 52 , 458-64, (2008)

beta-D-2'-Deoxy-2'-fluoro-2'-C-methylcytidine (PSI-6130) is a potent inhibitor of hepatitis C virus (HCV) RNA replication in an HCV replicon assay. The 5'-triphosphate of PSI-6130 is a competitive inh...