4-Chloro-3-nitroanisole
Names
[ CAS No. ]:
10298-80-3
[ Name ]:
4-Chloro-3-nitroanisole
[Synonym ]:
4-chloro-3-nitrophenyl methyl ether
2-Chloro-5-Methoxynitrobenzene
1-Chloro-2-nitro-4-methoxybenzene
4-Chloro-3-nitroanisole
dioxoaMine
1-Chloro-4-methoxy-2-nitrobenzene
EINECS 233-674-1
4-methoxy-2-nitrochlorobenzene
2-fluoronitrobenzene
4-Chlor-3-nitro-anisol
MFCD00007077
3-NITRO-4-CHLOROANISOLE
4-chloro-3-nitro-anisol
2-Nitro-4-methoxychlorobenzene
Benzene, 1-chloro-4-methoxy-2-nitro-
4-chloro-3-nitro-anisole
Chemical & Physical Properties
[ Density]:
1.4±0.1 g/cm3
[ Boiling Point ]:
293.3±20.0 °C at 760 mmHg
[ Melting Point ]:
41-43 °C(lit.)
[ Molecular Formula ]:
C7H6ClNO3
[ Molecular Weight ]:
187.580
[ Flash Point ]:
131.2±21.8 °C
[ Exact Mass ]:
187.003616
[ PSA ]:
55.05000
[ LogP ]:
2.65
[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C
[ Index of Refraction ]:
1.560
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- BZ8580000
- CHEMICAL NAME :
- Anisole, 4-chloro-3-nitro-
- CAS REGISTRY NUMBER :
- 10298-80-3
- BEILSTEIN REFERENCE NO. :
- 0640872
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C7-H6-Cl-N-O3
- MOLECULAR WEIGHT :
- 187.59
- WISWESSER LINE NOTATION :
- WNR BG EO1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 180 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#04759
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xi:Irritant;
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
S26-S36
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
BZ8580000
[ HS Code ]:
29093090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2909309090
[ Summary ]:
2909309090 other aromatic ethers and their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%
Articles
Chem. Pharm. Bull. 48(1) , 131-9, (2000)
A group of derivatives of 7-methanesulfonylamino-6-phenoxychromone (1) at the pyrone and phenoxy rings was synthesized starting with 4-chloro-3-nitroanisole and evaluated against acute and chronic inf...