A40926

Names

[ Name ]:
A40926

[Synonym ]:
Pyrazino[2,1-a]pyrido[2,3-c][2]benzazepine, 1,2,3,4,10,14b-hexahydro-2-methyl-
Zispin
UNII:A051Q2099Q
2-Methyl-1,2,3,4,10,14b-hexahydropyrazino[2,1-a]pyrido[2,3-c][2]benzazepine
2-Methyl-1,2,3,4,10,14b-hexahydrobenzo[c]pyrazino[1,2-a]pyrido[3,2-f]azepine
Avanza
Remeron
A40926

Biological Activity

[Description]:

A40926, the precursor of Dalbavancin, is a second-generation glycopeptide antibiotic. A40926 inhibits gram-positive bacteria, and is very active against Neisseria gonorrhoeae[1].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Bacterial

[References]

[1]. Goldstein BP, et al. A40926, a new glycopeptide antibiotic with anti-Neisseria activity.Antimicrob Agents Chemother. 1987 Dec;31(12):1961-6.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
432.4±45.0 °C at 760 mmHg

[ Melting Point ]:
>160℃ (dec.)

[ Molecular Formula ]:
C₈₃H₈₆Cl₂N₈O₃₀

[ Molecular Weight ]:
265.353

[ Flash Point ]:
215.3±28.7 °C

[ Exact Mass ]:
265.157898

[ LogP ]:
2.75

[ Vapour Pressure ]:
0.0±1.0 mmHg at 25°C

[ Index of Refraction ]:
1.668

Related Compounds

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