SW-106
Names
[ CAS No. ]:
1027921-53-4
[ Name ]:
SW-106
Biological Activity
[Description]:
A potent, selective, competitive PTH/PTH-related peptide receptor (PPR) antagonist with IC50 of 0.99 uM; displays higher affinity for the PPR relative to the other GPCRs; specificly blocks PTH-initiated cAMP accumulation.
[References]
References 1. Carter PH, et al. Proc Natl Acad Sci U S A. 2007 Apr 17;104(16):6846-51. 2. Carter PH, et al. Mol Endocrinol. 2015 Feb;29(2):307-21. View Related Products by Target PTH Receptor
Chemical & Physical Properties
[ Molecular Formula ]:
C17H16F5NO2
[ Molecular Weight ]:
361.312