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2-DEOXY-ALPHA-D-RIBOSE 1-PHOSPHATE BIS(CYCLOHEXYLAMINE) SALT

Names

[ CAS No. ]:
102783-28-8

[ Name ]:
2-DEOXY-ALPHA-D-RIBOSE 1-PHOSPHATE BIS(CYCLOHEXYLAMINE) SALT

Chemical & Physical Properties

[ Molecular Formula ]:
C17H37N2O7P

[ Molecular Weight ]:
412.45900

[ Exact Mass ]:
412.23400

[ PSA ]:
178.30000

[ LogP ]:
2.52010

[ Storage condition ]:
-20°C

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Safety Phrases ]:
22-24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Articles

The role of thymidine phosphorylase, an angiogenic enzyme, in tumor progression.

Cancer Sci. 95(11) , 851-7, (2004)

Thymidine phosphorylase (TP), an enzyme involved in pyrimidine metabolism, is identical with an angiogenic factor, platelet-derived endothelial cell growth factor (PD-ECGF). TP is overexpressed in var...

The kinetic mechanism of Human Thymidine Phosphorylase - a molecular target for cancer drug development.

Mol. Biosyst. 10(3) , 592-604, (2014)

Human Thymidine Phosphorylase (HTP), also known as the platelet-derived endothelial cell growth factor (PD-ECGF) or gliostatin, catalyzes the reversible phosphorolysis of thymidine (dThd) to thymine a...

Efficient chemo-enzymatic syntheses of pharmaceutically useful unnatural 2'-deoxynucleosides.

Nucleosides Nucleotides Nucleic Acids 24(5-7) , 1127-30, (2005)

Our chemo-enzymatic method was successfully applied to the synthesis of 2-chloro-2'-deoxyadenosine (CdA, cladribine) in two ways: 1) direct conversion of chemically synthesized 2-deoxy-alpha-D-ribose ...


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Related Compounds

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