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Saterinone hydrochloride

Names

[ CAS No. ]:
102685-83-6

[ Name ]:
Saterinone hydrochloride

Biological Activity

[Description]:

Saterinone hydrochloride is a phosphodiesterase III (PDE III) inhibitor.

[Related Catalog]:

Signaling Pathways >> Metabolic Enzyme/Protease >> Phosphodiesterase (PDE)
Research Areas >> Cardiovascular Disease

[Target]

phosphodiesterase III (PDE III)[1]


[In Vitro]

Saterinone combines direct positive inotropic action with pronounced vasodilating properties partly due to an alpha-receptor antagonism of its urapidil-like moiety in the molecular structure[1].

[References]

[1]. Kieback AG, et al. Pharmacokinetics and hemodynamic effects of the phosphodiesterase III inhibitor saterinone in patients with chronic heart failure. Int J Cardiol. 2003 Oct;91(2-3):201-8.


[Related Small Molecules]

3-Isobutyl-1-methylxanthine | rolipram | PF-04957325 | AN-2728 | GLPG1690 | BAY-60-7550 | Icariin | Ibudilast | PF-8380 | TAK-063 | Dipyridamole | Cilostazol | GSK256066 | Cialis | Pentoxifylline

Chemical & Physical Properties

[ Molecular Formula ]:
C27H31ClN4O4

[ Molecular Weight ]:
511.01


Related Compounds

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