AA-dUTP sodium salt

Names

[ Name ]:
AA-dUTP sodium salt

[Synonym ]:
5br-dutp sodium salt
brdutp
5-bromo-2'-deoxyuridine 5'-triphosphate
5-bromo-2'-deoxyuridine 5'-triphosphate sodium
AA-dUTP sodium salt

Biological Activity

[Description]:

5-BrdUTP sodium salt is a TdT substrate which can be used to label the DNA double-strand breaks.

[Related Catalog]:

Signaling Pathways >> Others >> Others

Dye Reagents

Research Areas >> Others

[References]

[1]. Darzynkiewicz Z, et al. Detection of DNA strand breaks in apoptotic cells by flow- and image-cytometry. Methods Mol Biol. 2011;682:91-101.

[Related Small Molecules]

Chemical & Physical Properties

[ Molecular Formula ]:
C₉H₁₄BrN₂Na₄O₁₄P₃

[ Molecular Weight ]:
639.00

[ PSA ]:
273.57000

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges

[ Hazard Codes ]:
T: Toxic;

[ Risk Phrases ]:
R23/24/25

[ Safety Phrases ]:
22-26-36-45

[ RIDADR ]:
NONH for all modes of transport

Articles

Visualizing the dynamics of chromosome structure formation coupled with DNA replication.

Chromosoma 116 , 453-462, (2007)

A basic question of cell biology is how DNA folds to chromosome. Numbers of examples have suggested the involvement of DNA replication in chromosome structure formation. To visualize and identify the ...

Insights into the mechanisms of sister chromatid exchange formation.

Cytogenet. Genome Res. 104 , 304-309, (2004)

The DNA lesions responsible for the formation of sister chromatid exchanges (SCEs) have been the object of research for a long time. SCEs can be visualized by growing cells for either two rounds of re...

The mutagenic properties of BrdUTP in a random mutagenesis process.

Mol. Biol. Rep. 35 , 663-667, (2008)

To explore the mutagenic properties of the nucleotide analogue bromodeoxyuridine triphosphate (BrdUTP), the wild type alpha-amylase (xamy) gene from Xanthomonas campestris pv. campestris 8004 was used...