2-(4-(2-(4-(2,2-DIMETHYLBUTYL)-1H-IMIDAZOL-2-YL)ETHYL)PHENYL)PYRIDINE

Names

[ CAS No. ]:
1021937-07-4

[ Name ]:
2-(4-(2-(4-(2,2-DIMETHYLBUTYL)-1H-IMIDAZOL-2-YL)ETHYL)PHENYL)PYRIDINE

[Synonym ]:
Bag-1

Biological Activity

[Description]:

BRS-3 receptor agonist-2 (compound 2) is a potent BRS-3 receptor agonist, with an EC50 of 2.5 nM for mouse BRS-3 receptor[1].

[Related Catalog]:

Signaling Pathways >> GPCR/G Protein >> Bombesin Receptor

Research Areas >> Neurological Disease

[Target]

EC50: 2.5 nM (mouse BRS-3 receptor)[1]

[References]

[1]. Chobanian HR, et, al. Discovery of MK-7725, A Potent, Selective Bombesin Receptor Subtype-3 Agonist for the Treatment of Obesity. ACS Med Chem Lett. 2012 Jan 21;3(3):252-6.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₂H₂₇N₃

[ Molecular Weight ]:
333.47

[ Exact Mass ]:
333.22000

[ PSA ]:
41.57000

[ LogP ]:
5.23560

Safety Information

[ HS Code ]:
2933990090

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%