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(S)-O-Desmethyl Venlafaxine N-Oxide

Names

[ CAS No. ]:
1021934-03-1

[ Name ]:
(S)-O-Desmethyl Venlafaxine N-Oxide

Biological Activity

[Description]:

(S)-O-Desmethyl Venlafaxine N-Oxide is a N-oxyde of (S)-O-Desmethyl Venlafaxine. O-Desmethyl Venlafaxine is an active metabolite of Venlafaxine[1]. Venlafaxine (HY-B0196) is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class[2].

[Related Catalog]:

Research Areas >> Neurological Disease

[References]

[1]. Lechoslaw A. Turski, et al. N-oxydes de venlafaxine et de o-desméthylvenlafaxine comme promédicaments. WO2009000797A1.

[2]. Yijin Liu, et al. Development of an enantioselective assay for simultaneous separation of venlafaxine and O-desmethylvenlafaxine by micellar electrokinetic chromatography-tandem mass spectrometry: Application to the analysis of drug-drug interaction. J Chromatogr A. 2015 Nov 13;1420:119-28.

[3]. F P Bymaste, et al. Comparative affinity of duloxetine and venlafaxine for serotonin and norepinephrine transporters in vitro and in vivo, human serotonin receptor subtypes, and other neuronal receptors. Neuropsychopharmacology. 2001 Dec;25(6):871-80.

Chemical & Physical Properties

[ Molecular Formula ]:
C16H25NO3

[ Molecular Weight ]:
279.37

[ Storage condition ]:
-20°C

Related Compounds