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Cefacetrile

Names

[ CAS No. ]:
10206-21-0

[ Name ]:
Cefacetrile

[Synonym ]:
cefacetrile

Biological Activity

[Description]:

Cefacetrile (Cephacetrile) is a broad-spectrum antibiotic that is effective in gram-positive and gram-negative bacterial infection[1][2].

[Related Catalog]:

Research Areas >> Infection
Signaling Pathways >> Anti-infection >> Bacterial

[In Vitro]

Cefacetrile (less than 1 μg/mL) inhibits Staphylococcus aureusand Streptococcus pyogenes[2].

[In Vivo]

Cefacetrile (50, 100 and 500 mg/kg, s.c.) does not alter fertility, gestation and post-natal development of term foetuses of rats and fertility and gestation of rabbits[3]. Cefacetrile (1 g/kg, i.v.) produces no nephrotoxicity in rabbits and rats[4].

Chemical & Physical Properties

[ Density]:
1.59g/cm3

[ Boiling Point ]:
757.5ºC at 760mmHg

[ Melting Point ]:
133-135°C

[ Molecular Formula ]:
C13H13N3O6S

[ Molecular Weight ]:
339.32400

[ Flash Point ]:
412ºC

[ Exact Mass ]:
339.05300

[ PSA ]:
162.10000

[ Vapour Pressure ]:
4.02E-25mmHg at 25°C

[ Index of Refraction ]:
1.639

[ Storage condition ]:
Hygroscopic, -20?C Freezer, Under Inert Atmosphere


Related Compounds

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