(3S)-1-Benzyl-3-methylpyrrolidine

Names

[ Name ]:
(3S)-1-Benzyl-3-methylpyrrolidine

[Synonym ]:
S-(-)-1-Benzyl-3-pyrrolidinol
Pyrrolidine, 3-methyl-1-(phenylmethyl)-, (3S)-
(3S)-1-benzylpyrrolidin-3-ol
MFCD00075485
(S)-1-Benzyl-3-hydroxypyrrolidine
(S)-1-Benzylpyrrolidin-3-ol
(S)-1-Benzyl-3-pyrrolidinol
(S)-(−)-1-Benzyl-3-pyrrolidinol
(3S)-1-Benzyl-3-methylpyrrolidine
(S)-(-)-1-Benzyl-3-pyrrolidinol
EINECS 212-273-5

Biological Activity

[Description]:

(S)-1-Benzylpyrrolidin-3-ol (Compound 14) can be used to synthesis impurities of the anti-hypertensive drug Barnidipine hydrochloride (HY-107322)[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Cheng ZG, et al . Synthesis and characterization of impurities of barnidipine hydrochloride, an antihypertensive drug substance. Molecules. 2014 Jan 21;19(1):1344-52.

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
237.3±9.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₁H₁₅NO

[ Molecular Weight ]:
175.270

[ Flash Point ]:
88.7±15.6 °C

[ Exact Mass ]:
175.136093

[ PSA ]:
23.47000

[ LogP ]:
2.68

[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.540

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xi:Irritant

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%