2-Methoxy-4-nitrobenzonitrile

[ Density]:
1.324g/cm3

[ Boiling Point ]:
364.545ºC at 760 mmHg

[ Melting Point ]:
177-180ºC(lit.)

[ Molecular Formula ]:
C₈H₆N₂O₃

[ Molecular Weight ]:
178.14500

[ Flash Point ]:
174.271ºC

[ Exact Mass ]:
178.03800

[ PSA ]:
78.84000

[ LogP ]:
1.99828

[ Vapour Pressure ]:
0mmHg at 25°C

[ Index of Refraction ]:
1.563

Click to get detail MSDS

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H312-H315-H319-H332-H335

[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
R20/21/22

[ Safety Phrases ]:
S26

[ RIDADR ]:
UN3439

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1

[ HS Code ]:
2926909090

Click to get detail synthetic route

Precursor

DownStream

[ HS Code ]: 2926909090

[ Summary ]:
HS:2926909090 other nitrile-function compounds VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Development of 2-thioxoquinazoline-4-one derivatives as dual and selective inhibitors of dynamin-related protein 1 (Drp1) and puromycin-sensitive aminopeptidase (PSA).

Chem. Pharm. Bull. 62(10) , 979-88, (2014)

An established inhibitor of dynamin-related protein 1 (Drp1), 3-(2,4-dichloro-5-methoxyphenyl)-2-thioxoquinazoline-4-one (mdivi-1), was recently reported also to show potent puromycin-sensitive aminop...

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