4′-Chloroacetoacetanilide
Names
[ CAS No. ]:
101-92-8
[ Name ]:
4′-Chloroacetoacetanilide
[Synonym ]:
4‘-Chloroacetoacetanilide
4'-Chloroacetoacetan
GR DMV1V1
N-(4-Chlorphenyl)-3-oxobutanamide
3-oxo-N-(4'-chlorophenyl)butanamide
MFCD00000613
N-(4-Chlorophenyl)acetoacetamide
N-(4-methoxyphenyl)-3-oxobutanamide
p-Acetoacetchloranilide
Acetoacetanilide, 4'-chloro-
P-CHLOROACETOACETANILIDE
Butanamide, N-(4-chlorophenyl)-3-oxo-
N-Acetoacetyl-4-chloroaniline
PARA-CHLOROACETOANILIDE
Acetoacetanilide, p-chloro-
EINECS 202-989-6
N-(4-Chlorophenyl)-3-oxobutanamide
AAPCA
N-(4-chlorophenyl)-3-oxobutyramide
Acetoacet-p-chloroanilide
4′-Chloroacetoacetanilide
4'-Chloroacetoacetanilide
p-chlorodiacetanilide
4'-CHLOROACETACETANILIDE
Chemical & Physical Properties
[ Density]:
1.3±0.1 g/cm3
[ Boiling Point ]:
400.5±30.0 °C at 760 mmHg
[ Melting Point ]:
131-134 °C(lit.)
[ Molecular Formula ]:
C10H10ClNO2
[ Molecular Weight ]:
211.645
[ Flash Point ]:
196.0±24.6 °C
[ Exact Mass ]:
211.040009
[ PSA ]:
46.17000
[ LogP ]:
1.82
[ Vapour Pressure ]:
0.0±0.9 mmHg at 25°C
[ Index of Refraction ]:
1.579
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- AK4375000
- CHEMICAL NAME :
- Acetoacetanilide, 4'-chloro-
- CAS REGISTRY NUMBER :
- 101-92-8
- BEILSTEIN REFERENCE NO. :
- 1819161
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C10-H10-Cl-N-O2
- MOLECULAR WEIGHT :
- 211.66
- WISWESSER LINE NOTATION :
- GR DMV1V1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CBCCT* "Summary Tables of Biological Tests," National Research Council Chemical-Biological Coordination Center. (National Academy of Science Library, 2101 Constitution Ave., NW, Washington, DC 20418) Volume(issue)/page/year: 4,225,1952
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ Hazard Codes ]:
Xi
[ Safety Phrases ]:
S24/25
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
1
[ RTECS ]:
AK4375000
[ HS Code ]:
2924299090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2924299090
[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%
Articles
Chem. Res. Toxicol. 16(10) , 1338-58, (2003)
A number of environmental and industrial chemicals are reported to possess androgenic or antiandrogenic activities. These androgenic endocrine disrupting chemicals may disrupt the endocrine system of ...
Preparation of 4-anilino-6-aryl-2 H-pyran-2-ones from trilithiated acetoacetanilides and aromatic esters. Downs JR, et al.Can. J. Chem. 82(5) , 659-664, (2004)
Synthesis and antimicrobial activity of n, 7-diaryl-5-methyl-4, 7-dihydrotetrazolo [1, 5-a] pyrimidine-6-arboxamides. Gein VL, et al.
Pharmaceut. Chem. J. 44(7) , 366-369, (2010)